How COVID-19 Is Changing Respiratory Testing Algorithms

As healthcare evolves through the pandemic, labs are strategically incorporating SARS-CoV-2 into routine testing

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The COVID-19 pandemic has shaped our lives for more than a year, and one thing is certain: SARS-CoV-2 isn’t going away anytime soon. In fact, with concerns over emerging strains and lingering questions about whether vaccinated individuals can still be contagious, accurate diagnostic test results will continue to be essential.

Clinical algorithms used for respiratory tests continue to evolve, especially after accommodating the continuous presence of COVID-19 for more than a year now. Additionally, since many symptoms of COVID-19 overlap with those seen in influenza, respiratory syncytial virus (RSV), and other respiratory illnesses, testing has been one of the most challenging aspects of the pandemic. Influenza in particular shares several symptoms also seen in COVID-19, including fever, cough, difficulty breathing, fatigue, and more—all with varying degrees of severity.

Although there are other important differences between COVID-19 and other respiratory illnesses, testing is the best way to determine a diagnosis. Since the beginning of the outbreak, lab teams have had a need for reliable respiratory panels that include not only influenza A/B and RSV, but also SARS-CoV-2.

Respiratory panels offer several benefits compared to single-target tests

Beyond diagnostic confirmation, there are benefits to using a test that combines SARS-CoV-2 detection with testing for other respiratory infections. Running a single combination test is more comfortable for the patient since only one sample is needed, and with one streamlined workflow to get results for multiple targets, it ends up being more efficient for the lab as well, saving both time and resources.

Outside of flu season, it will still be important to include SARS-CoV-2 in regular respiratory infection testing. Ideally, the virus would be added to all standard respiratory panels used by clinical labs throughout the year, as well as to small, targeted panels for specific seasons and for vulnerable patient populations.

Of course, standalone testing for SARS-CoV-2 will continue to be important as well—particularly for back-to-work and back-to-school testing, before surgical procedures, and for other routine screening not based on specific respiratory symptoms.

With the ongoing increased need for flexible and comprehensive diagnostic testing tools, we’re working hard to help ensure clinical labs have options for managing SARS-CoV-2 testing in the long term. For targeted SARS-CoV-2 testing, we developed the ® Respiratory Pathogen Panel + SARS-CoV-2″ href=”/nxtag-respiratory-pathogen-panel-sars-cov-2/”>NxTAG® Respiratory Pathogen Panel + SARS-CoV-2 (EUA, CE-IVD) and the ® SARS-CoV-2 Antibody Assay” href=”/xmap-sars-cov-2-antibody-testing/#overview”>xMAP® SARS-CoV-2 Antibody Assay (EUA) enables the identification of antibodies against SARS-CoV-2 in serum. With additional plans to continue adding the SARS-CoV-2 target to our existing assays, it’s safe to say whatever your testing needs are, we have a solution for you.

For more information about our latest COVID-19 offerings, check out our website.

Learn More About Our Latest COVID-19 Offerings.

(EUA) In Vitro Diagnostic Use Under Emergency Use Authorization. This test has not been FDA cleared or approved. This test has been authorized by the FDA under an EUA for use by authorized laboratories.
(CE-IVD) For In Vitro Diagnostic Use. Products are region specific and may not be approved in some countries/regions.

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