Webinar: Fast, Economical Malaria Testing with xMAP® Technology

Multiplex assay allows for detailed investigations of transmission and drug resistance

Multiplexing technology from Luminex has been critical for the development of assays designed to study human SNPs involved in parasite transmission as well as the spread of drug resistance markers in Plasmodium falciparum. That was a key message in this presentation from Lynn Grignard, a research fellow at the London School of Hygiene and Tropical Medicine.

Malaria, which led to 212 million cases worldwide in 2015, is caused by a parasite with a remarkably complex life cycle. Important steps include development in the mosquito and transmission to a human host when the mosquito feeds, followed by a liver cycle and blood stage within the human. While malaria is preventable and curable, Grignard said, it remains a life-threatening disease, particularly in Africa.

Developing Assays

In her presentation, Grignard focused on two areas she studies: how human SNPs are involved in transmission or protection against malaria, and how drug resistance is spread to the parasite. These investigations led to the development of two assays based on ® Technology” href=”https://www.youtube.com/watch?v=m6DvXhtFOm4″>Getting Started with xMAP® Technology [Video]

  • ® Cookbook to Design Your Own Assays” href=”http://info.luminexcorp.com/en-us/research/download-the-xmap-cookbook”>xMAP® Cookbook to Design Your Own Assays [Download]
  • An Expert’s Guide to Multiplexing Immunoassays [Blog]
  • Multiplex Malaria MagPlex-TAG Assay to Detect Human Host and Parasite Genetic Markers